Sleep, Negentropy and Consciousness

Authors

  • Michael Remler VAMC, 150 Muir Rd., Martinez, CA 94553 USA
10.5281/zenodo.21818356

Abstract

Circadian rhythms of alternating metabolic patterns homologous to those seen in the human sleep wake cycle are ubiquitous in virtually all life forms. Negative entropy metabolic activity, negentropy, the importation of high energy compounds and the elimination of low energy residua, used to maintain a low internal entropy environment is similarly ubiquitous. The metabolic cycle, as internalized across the life forms, functions to sequester portions of the negative entropy process which would interfere with each other if attempted simultaneously. Information is the essence of low entropy. Evolution is associated with the progressive increase in the direct importation of information and the utilization of that information to maintain low internal entropy. While 'Information is Physical', its management and storage, requires energy, alternative stored information do not differ in enthalpy but only in meaning. The only way to process and store information negentropy is to be aware of the information, understand the information, have the free will to choose and the ability to control the matter of the brain to affect that choice. The capacities which define the essence of Consciousness, are the same as those essential for Information Negentropy. In humans, the process that manages negentropy through wakefulness and sleep is continuous in its identity, also through some coma, dementia and some psychosis. The deeper understanding of Consciousness must transcend not only its various modes of function but more so its necessity to understand meaning in order to perform negentropy.

Keywords:

Sleep, Negentropy, Consiousness, Information, Encephalization

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References

Alter, Torin, Pereboom D. Russellian Monism. The Stanford Encyclopedia of Philosophy. 2023; Edition), Edward N. Zalta & Uri Nodelman (eds.),

Bennett CH. Notes on Landauer's principle, Reversible Computation and Maxwell's Demon, Studies in History and Philosophy of Modern Physics. 2003;34 (3): 501–510.

Chalmers, David, Facing up to the problem of consciousness. Journal of Consciousness Studies 1995; 2(3):200-19

Davies PC, Rieper E, Tuszynski JA. Self-organization and entropy reduction in a living cell. Biosystems 2013;111(1):1-10.

Diekelmann S, Born J. The memory function of sleep. Nature Reviews Neuroscience 2010;11(2):114-26.

Draguhn A, Mallatt JM, Robinson DG. Anesthetics and plants: no pain, no brain, and therefore no consciousness. Protoplasma 2021;258(2):239-248.

Eckel-Mahan K, Sassone-Corsi P. Metabolism and the circadian clock converge. Physiology Review. 2013;93(1):107-35.

Foyer CH, Noctor G. Redox regulation in photosynthetic organisms: signaling, acclimation, and practical implications. Antioxid Redox Signal 2009;11(4):861-905.

Freud, S. The Unconscious. The Standard Edition of the Complete Psychological Works of Sigmund Freud 1915;14:159-215

Geschwind N. Disconnexion syndromes in animals and man. I. Brain 1965;88(2):237–294.

Givental A, private communication.

Goff P, Seager W, Allen-Hermanson S. Panpsychism, The Stanford Encyclopedia of Philosophy, Edward N. Zalta (ed.), 2022.

Grzywacz NM. Perceptual Complexity as Normalized Shannon Entropy. Entropy (Basel). 2025;27(2):166.

Gumz RJ. Mechanism of the circadian clock in physiology. American Journal Physiology Regulatory, Integrative and Comparative Physiology 2013;15;304(12):R1053-64.

Hazen RM, Wong ML, Time's Second Arrow; Evolution, Order, and a New Law of Nature, W W Norton and Co. 2026.

He C, Zhou P, Nie Q. exFINDER: identify external communication signals using single-cell transcriptomics data. Nucleic Acids Research 2023;51(10):e58.

IBM. https://www.ibm.com/think/topics/ai-model. 2026

Jaggard JB, Wang GX, Mourrain P. Non-REM and REM/Paradoxical sleep dynamics across phylogeny. Current Opinion in Neurobiology 2021;71:44-51

Kennedy MB. Synaptic Signaling in Learning and Memory. Cold Spring Harbor Perspectives in Biology 2013 Dec 30;8(2):a016824.

Kim J, Park M. Systems memory consolidation during sleep: oscillations, neuromodulators, and synaptic remodeling. BMB Reports 2025;58(10):425-436.

Koch K, McLean J, Segev R, Freed MA, Berry II MJ, Balasubramanian V, Sterling P. How Much the Eye Tells the Brain. Volume 16, Issue 14, 2006;1428-1434.

Landauer R. Information is Physical. Physics Today. 1991;44, 5, 23.

Loudon AS. Circadian biology: a 2.5 billion year old clock. Curr Biol 2012;22(14): R570-1.

Lutz ND, Harkotte M, Born J. Sleep's contribution to memory formation. Physiological Reviews 2025;106:1, 363-483.

Mills JN, Minors DS, Waterhouse JM. The circadian rhythms of human subjects without timepieces or indication of the alternation of day and night. J Physiol 1974;240(3):567-94.

Makarieva AM, Gorshkov VG, Li BL, Chown SL, Reich PB, Gavrilov VM. Mean mass-specific metabolic rates are strikingly similar across life's major domains: Evidence for life's metabolic optimum. Proc Natl Acad Sci U S A. 2008:4;105(44):16994-9.

Marx G, Gilon C. The molecular basis of memory. ACS Chem Neurosci. 2012;15;3(8):633-42.

McCulloch W, Embodiments of Mind. 2016. MIT Press

Nowak N, Gaisl T, Miladinovic D, Marcinkevics R, Osswald M, Bauer S, Buhmann J, Zenobi R, Sinues P, Brown SA, Kohler M. Rapid and reversible control of human metabolism by individual sleep states. Cell Rep. 2021 Oct 26;37(4):109903.

Omond SET, Lesku JA. Why study sleep in flatworms? J Comp Physiol B 2024;194(3):233-239.

Ornes S. Core Concept: How nonequilibrium thermodynamics speaks to the mystery of life. Proc Natl Acad Sci USA 2017;114(3):423-424.

Paller KA, Creery JD, Schechtman E. Memory and Sleep: How Sleep Cognition Can Change the Waking Mind for the Better. Annu Rev Psychol 2021;72:123-150.

Raichle ME, Gusnard DA. Appraising the brain's energy budget. Proc Natl Acad Sci USA 2002 Aug 6;99(16):10237-9.

Remler M. Quantum Mechanics as Scientific Panpsychism. Journal of NeuroPhilosophy 2026;5(1):174-187.

Resmini A, Rosati L, Pervasive Information Architecture, Designing Cross-Channel User Experiences Elsevier 2011.

Rutter J, Reick M, McKnight SL. Metabolism and the control of circadian rhythms. Annual Review of Biochemistry 2002;71:307-31.

Schrödinger, E. What is Life? Mind and Matter. United Kingdom: Cambridge University Press. 1967.

Schrödinger, E., Oesterreichische Akademie der Wissenschaften, Vienna. Erwin Schrödinger: Collected papers V. 4. General scientific and popular papers. 1984. Verlag der Oesterreichischen Akademie der Wissenschaften.

Strawson G, Consciousness and Its Place in Nature: Why Physicalism Entails Panpsychism, 2nd Edition Paperback, Anthony Freeman (Editor) 2022.

Sulaman BA, Wang S, Tyan J, Eban-Rothschild A. Neuro-orchestration of sleep and wakefulness. Nat Neurosci 2023 Feb;26(2):196-212.

Thorup E. The Neuroscience of Memory: How the Brain Stores and Retrieves Information. Neuroscience and Psychiatry: Open Access 2024; DOI: 10.47532/npoa.2024.7(6).297-299

Velez-Ramirez I, van Ieperen Wlm, Vreugdenhil D, Millenaar FF. Plants under continuous light, Trends in Plant Science 2011; 16(6): 310-318.

Venkat A, Muneer S. Role of Circadian Rhythms in Major Plant Metabolic and Signaling Pathways. Front Plant Sci 2022;13:836244.

Zheng J, Meister M. The Unbearable Slowness of Being: Why do we live at 10 bits/s? arXiv: 2024;2408.10234;

Zones JM, Blaby IK, Merchant SS, Umen JG. High-Resolution Profiling of a Synchronized Diurnal Transcriptome from Chlamydomonas reinhardtii Reveals Continuous Cell and Metabolic Differentiation. Plant Cell 2015 Oct;27(10):2743-69.

Published

06.08.2026

How to Cite

Remler, M. (2026). Sleep, Negentropy and Consciousness. Journal of NeuroPhilosophy, 5(2). https://doi.org/10.5281/zenodo.21818356