The Posterior Cingulate Cortex Again Forgotten




Koch et al., (2022) 'Repetitive TMS applied to the precuneus stabilizes cognitive status in Alzheimer's disease,' we think that some findings are misunderstood and there are methodological problems. Neuromodulation approaches have been investigated for a long time in the treatment of Alzheimer's dementia. On the other hand, the precuneus region, which is the subject of the research, cannot be considered as an isolated region due to its close neighborhood. Precuneus, it is considered the main center of the default mode network (DMN) like the prefrontal cortex (DLPFC). To date, many DLPFC stimulation studies have been performed with repetitive transcranial magnetic stimulation (rTMS) has been published. It is difficult to evaluate the effect claimed as a result of the research specific to the precuneus region. Theoretically, the effect can be expected with the excitation of any part of the default network. However, unlike previous rTMS studies that stimulated the DLPFC, the authors chose to stimulate the precuneus, the main center of DMN.


mind, brain, DLPFC, cingulate cıetex, repetitive transcranial magnetic stimulation, rTMS, default mode network, DMN, precuneus


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Author Biography

Sultan Tarlacı

He was awarded a Research Encouragement Award by the Society of Brain Research (2000), a Research Encouragement Award by TUBITAK Society of Brain Research (2001), the Sedat Simavi Health Sciences Award by the Society of Turkish Journalists (2003), NeoCortex Prize (2014). He is the author of a medical textbook titled Neurologic Emergency Disease: Current Diagnosis and Treatment (2011) and four recently published popular books titled Crime and Brain (2017), From Cave to Mars (2017), Death’Dic (2016), Why Schrödinger's cat became schizophrenic? (2016) and NeuroQuantology (New York, 2014). His main research interest is the application of quantum physics to the nervous system, neuropsychology, neurophilosophy and clinical electrophysiology.


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How to Cite

Tarlacı, S. (2023). The Posterior Cingulate Cortex Again Forgotten. Journal of NeuroPhilosophy, 2(1).